Antibody Engineering Methods and Protocols

ISBN: 1588290921

Category: Uncategorized


Posted on 2019-03-24, updated at 2019-05-09, by voska89.

Description


1903231314570108.jpg
Benny K. C. Lo, "Antibody Engineering: Methods and Protocols"
2003 | pages: 549 | ISBN: 1588290921 | PDF | 5,6 mb




The exquisite binding specificity of antibodies has made them valuable tools from the laboratory to the clinic. Since the description of the murine hybridoma technology by Köhler and Milstein in 1975, a phenomenal number of mo- clonal antibodies have been generated against a diverse array of targets. Some of these have become indispensable reagents in biomedical research, while others were developed for novel therapeutic applications. The attractiveness of an- bodies in this regard is obvious―high target specificity, adaptability to a wide range of disease states, and the potential ability to direct the host's immune s- tem for a therapeutic response. The initial excitement in finding Paul Ehrlich's "magic bullet," however, was met with widespread disappointment when it was demonstrated that murine antibodies frequently elicit the human anti-murine an- body (HAMA) response, thus rendering them ineffective and potentially unsafe in humans. Despite this setback, advances in recombinant DNA techniques over the last 15-20 years have empowered the engineering of recombinant antibodies with desired characteristics, including properties to avoid HAMA. The ability to p- duce bulk quantities of recombinant proteins from bacterial fermentation also fueled the design of numerous creative antibody constructs. To date, the United States Food and Drug Administration has approved more than 10 recombinant antibodies for human use, and hundreds more are in the development pipeline. The recent explosion in genomic and proteomic information appears ready to deliver many more disease targets amenable to antibody-based therapy.

Buy Premium From My Links To Get Resumable Support,Max Speed & Support Me

Download (Uploadgig)
https://uploadgig.com/file/download/b7c8bCc6002e0a07/gcdj7.Antibody.Engineering.Methods.and.Protocols.rar
Download ( Rapidgator )
https://rapidgator.net/file/9d57a05e4c0f0c8124e919a91aebb92d/gcdj7.Antibody.Engineering.Methods.and.Protocols.rar
Download ( NitroFlare )
http://nitroflare.com/view/44A03EF677891CE/gcdj7.Antibody.Engineering.Methods.and.Protocols.rar


Sponsored High Speed Downloads
5454 dl's @ 2958 KB/s
Download Now [Full Version]
7338 dl's @ 3650 KB/s
Download Link 1 - Fast Download
7281 dl's @ 3330 KB/s
Download Mirror - Direct Download



Search More...
Antibody Engineering Methods and Protocols

Search free ebooks in ebookee.com!


Related Archive Books

Archive Books related to "Antibody Engineering Methods and Protocols":



Links
Download this book

No active download links here?
Please check the description for download links if any or do a search to find alternative books.


Related Books


Comments

No comments for "Antibody Engineering Methods and Protocols".


    Add Your Comments
    1. Download links and password may be in the description section, read description carefully!
    2. Do a search to find mirrors if no download links or dead links.
    Back to Top