[PDF] Oncogene and Cancer: From Bench to Clinic

ISBN: f61cadc8ec

Category: Tutorial


Posted on 2017-10-18, by luongquocchinh.

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Author: Yahwardiah Siregar | Publisher: ITAe | Category: Medicine | Language: English | Page: 496 | ISBN: af61cadc8ecc4e5f860db1642f7c90ea |

Description: This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence. How to treat cancer more effectively and the problems like drug resistance and metastasis are very clearly illustrated in this publication as well as some research result that could be used to treat the cancer patients in the very near future. Contents Preface Section 1 HER2 Carcinogenesis: Etiology, Treatment and Prevention 1 Serial Changes in Expression of Proteins in Response to Neoadjuvant Chemotherapy in Breast Cancer 2 HER2-Driven Carcinogenesis: New Mouse Models for Novel Immunotherapies 3 HER2 Amplification or Overexpression in Upper Gl Tract and Breast Cancer with Clinical Diagnosis and Treatment Section 2 DNA Repair Mechanism and Cancer 4 Emerging Roles of Atypical Dual Specificity Phosphatases in Cancer 5 DNA Repair Molecules and Cancer Therapeutical Responses Section 3 A New Role of Oncogenes and Tumorsuppressorgenes 6 Structure-Based Approaches Targeting Oncogene Promoter G-Quadruplexes 7 Cancer Genes and Chromosome Instability 8 Human Papillomaviruses Oncoproteins Section 4 A New Approach on Cancer Mechanism 9 Model Systems Facilitating an Understanding of Mechanisms for Oncogene Amplification 10 MLL Gene Alterations in Acute Myeloid Leukaemia (11q23/MLL+ AML) 11 Dual Role ofTLR3 in Inflammation and Cancer Cell Apoptosis 12 A Different Approach for Cellular Oncogene Identification Came from Drosophila Genetics Section 5 Non Coding RNAand Micro RNAin Tumorigenesis 13 Post-Transcriptional Regulation of Proto-Oncogene c-fms in Breast Cancer 14 Non-Coding RNAs and Cancer 15 MiRNAand Proline Metabolism in Cancer 16 microRNA: New Players in Metastatic Process 17 Is CCDC26 a Novel Cancer-Associated Long-Chain Non-Coding RNA? Section 6 Oncogenes for Transcription Factors 18 The MYCN Oncogene 19 STAT Transcription Factors in Tumor Development and Targeted Therapy of Malignancies

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