[PDF] Pharmaceutical Process Scale-Up (Drugs and the Pharmaceutical Sciences)

ISBN: 0824706250

Category: Tutorial


Posted on 2018-01-14, by luongquocchinh.

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Author: Michael Levin | Publisher: CRC Press | Category: Medicine | Language: English | Page: 584 | ISBN: 0824706250 | ISBN13: 9780824706258 |

Description: Focusing on scientific and practical aspects of process scale-up, this resource details the theory and practice of transferring pharmaceutical processes from laboratory scale to the pilot plant and production scale. It covers parenteral and nonparenterel liquids and semi-solids, products derived from biotechnology, dry blending and powder handling, granulation and drying, fluid bed applications, compaction and tableting, and film coating and regulatory requirements for scale-up and postapproval changes. Drawing on the experience of twenty contributing researchers, the book employs dimensional analysis as a unified scientific approach to quantify similar processes on different scales.

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