[PDF] Phosphodiesterases and Their Inhibitors, Volume 61 (Methods and Principles in Medicinal Chemistry)

ISBN: 3527332197

Category: Tutorial


Posted on 2017-10-03, by luongquocchinh.

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Author: Spiros Liras, Andrew S. Bell, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers | Publisher: Wiley-VCH | Category: Chemistry | Language: English | Page: 240 | ISBN: 3527332197 | ISBN13: 9783527332199 |

Description: Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, pain, and allergy/respiratory diseases. Finally, emerging chemotherapeutic applications of PDE inhibitors against malaria and other tropical diseases are discussed.

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